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From the Cornerstone blog
Education on psychiatric treatment, ketamine, Spravato, and mental wellness from our clinical team.

Could Omega-3s Help Your Mental Health — and a Whole Lot More? What the Science Says
You might already know fish oil is ‘good for you.’ But the science goes much further than you think.
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Is Your Peptide Protocol Draining Your Brain Chemistry? What Biohackers Need to Know About Methylation
The landscape of personal health has shifted dramatically with the rise of direct-to-consumer peptide acquisition.
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SAM-e and Depression: What's Changed and What Patients Need to Know Now
General education content on SAM-e and depression treatment.
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Why Progesterone and SSRIs Can Both Work Quickly for PMDD, Sleep, and Anxiety
Many people are surprised that two very different treatments can help similar symptoms.
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Clearing Up the Confusion: L-Theanine, L-Threonine, and Magnesium L-Threonate in Psychiatric Use
Patients and clinicians alike are often confused by similarly named supplements that sound like they serve the same purpose.
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Psychedelic Integration and Grief: Why Healing Is Not Closure, but Continuity
One of the most enduring myths about grief is the belief that it ends in closure.
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Antiepileptic Drugs (AEDs), Folate, and Vitamin B12 Deficiency
Long-term use is associated with alterations in folate and vitamin B12 metabolism.
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Why Methylated B12 Is Often Paired With L-Methylfolate — Especially With Metformin or AEDs
B12 and folate are partners in one-carbon metabolism, essential for neurotransmitter synthesis.
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L-Methylfolate (5-MTHF) for Depression: Who Is Most Likely to Respond?
L-methylfolate is the biologically active form of folate that crosses the blood–brain barrier.
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Chaste Tree (Vitex agnus-castus) for PMS/PMDD: What to Know Before You Try It
General education content; not medical advice and does not create a clinician–patient relationship.
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Low-Dose Naltrexone (LDN): A Surprisingly Versatile Therapy for Pain, Autoimmunity, Mood, and Chronic Fatigue
General education content; not medical advice and does not create a clinician–patient relationship.
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Guide to Ketamine and NAD+: How They Work Together to Protect and Heal Your Brain
A simple guide to understanding how these two treatments team up to block damage and restore energy.
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Ketamine and the Kynurenine Pathway: A New Understanding of Depression Treatment
How a breakthrough anesthetic reveals the hidden metabolic roots of mental health challenges.
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The Best Magnesium for Sleep, Anxiety, and Mood
General education content; not medical advice and does not create a clinician–patient relationship.
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Unlocking the Potential of Glutamate in Depression Treatment
Depression is a complex condition with diverse underlying mechanisms.
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Everything You Need to Know About Spravato (Esketamine) for Treatment-Resistant Depression
Spravato targets glutamate differently than traditional antidepressants.
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Will Psych Providers Be Replaced by AI?
Artificial Intelligence is transforming industries everywhere, including healthcare and psychiatry.
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How ADHD Affects Relationships and What You Can Do About It
Common symptoms like distractibility, forgetfulness, and impulsivity often lead to misunderstandings.
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A Comprehensive Guide to the Top SAD Lamps of 2025
Seasonal Affective Disorder affects millions during darker winter months when sunlight is limited.
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The Synergistic Role of Serotonergic Medications in Augmenting Spravato and IV Ketamine Treatments
Ketamine-based therapies have revolutionized treatment of treatment-resistant depression.
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The Role of Concentration in GAD, MDD, and ADHD: A Shared Symptom Across Diagnoses
Concentration is an essential cognitive function allowing us to focus on tasks.
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Preparing for IV Ketamine or Spravato Treatment: A Comprehensive Guide
For individuals with treatment-resistant depression, IV ketamine addresses severe depressive symptoms.
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Spravato vs. IV Ketamine: Similarities and Differences in Treating Depression
The landscape of depression treatment has been significantly broadened with ketamine-based therapies.
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Exploring TMS: A Breakthrough for Patients with Treatment-Resistant Depression and OCD
In the landscape of mental health treatment, medication has long been the primary approach.
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Prominent Advocates for Ketamine in Mental Health Treatment
As understanding of mental health evolves, exploration of innovative treatments expands.
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IV Ketamine/NAD+ Combination Therapy: Exploring the Potential Synergy Between NAD+ and Ketamine in Treating Depression
Researchers delve into potential synergy between Nicotinamide Adenine Dinucleotide and Ketamine.
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Unlocking the Potential: How IV Infusions Can Improve Your Life
Is there a way to optimize your physical and mental health naturally and holistically?
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Medication Management for Seniors: Challenges and Solutions
Medication management poses several challenges for seniors living with mental health issues.
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Ketamine-Assisted Psychotherapy Is a New and Innovative Way to Treat Mental Healing
Are you struggling with mental health issues or feeling traditional treatments have been ineffective?
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What Is the Number One Rule to Losing Weight?
A look at sustainable habits for weight management.
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What's the Difference Between Telepsychiatry and Telehealth?
Telepsychiatry is a subset of telehealth using technology like phone and video conferencing.
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How Early Childhood Experiences Can Impact Mental Health Later in Life
We all want our children to have happy and healthy lives, but sometimes life doesn't go as planned.
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Bipolar Disorder vs. Depression: What's the Difference?
It can be difficult to differentiate between bipolar disorder and depression.
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The Surprising Success of Ketamine Treatments for Bi-Polar Depression
Depression is a severe mental health condition affecting millions annually in the United States.
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The Diet-Gut-Brain Axis
Although psychiatric disorders are primarily considered brain diseases, the digestive system influences brain health.
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A Technical Primer on Over-the-Counter Pregnenolone vs. Prescription Allopregnanolone
General education content; not medical advice and does not create a clinician–patient relationship.
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Patience, Coffee, and Gracefulness
The office has an awesome coffee pot; once described, your opinion of it may differ.
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Coping With Anxiety and Depression
You've heard the saying before: when life gives you lemons, make lemonade.
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Patient Perspective: “The Tears Would Just Come”
Uncontrollable crying for no reason was my sign to finally admit I needed help.
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Ketamine: Taking the Obsessions Out of Obsessive-Compulsive Disorder
Obsessive compulsive disorder has been subject to frequent indiscriminate use outside mental health.
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Depression and Sleep Problems
Major Depression is one of the most common mental health disorders.
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